Open AccessDrug the Bug!
Author(s) -
Annika Lindskog Jonsson,
Fredrik Bäckhed
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.12.005
Subject(s) - biology , gut flora , insulin resistance , disease , microbiome , gut microbiome , metabolism , obesity , medicine , endocrinology , immunology , bioinformatics
Microbial metabolism of dietary components has been causally linked to cardiovascular disease and atherosclerosis. Now, Wang et al. demonstrate that inhibition of microbial TMA lyases, essential for production of pro-atherogenic trimethylamines, prevents atherosclerosis in vivo.
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