Genome Sequencing Fishes out Longevity Genes
Author(s) -
Vanisha Lakhina,
Coleen T. Murphy
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.11.040
Subject(s) - biology , longevity , killifish , vertebrate , model organism , evolutionary biology , genome , genetics , gene , caenorhabditis elegans , fishery , fish <actinopterygii>
Understanding the molecular basis underlying aging is critical if we are to fully understand how and why we age-and possibly how to delay the aging process. Up until now, most longevity pathways were discovered in invertebrates because of their short lifespans and availability of genetic tools. Now, Reichwald et al. and Valenzano et al. independently provide a reference genome for the short-lived African turquoise killifish, establishing its role as a vertebrate system for aging research.
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