Open AccessGerminal Center Selection and the Antibody Response to Influenza
Author(s) -
Gabriel D. Victora,
Patrick C. Wilson
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.10.004
Subject(s) - biology , germinal center , virology , context (archaeology) , antibody response , selection (genetic algorithm) , influenza a virus , virus , immunity , antibody , immunology , immune system , b cell , artificial intelligence , computer science , paleontology
In this Minireview, we discuss basic aspects of germinal center biology in the context of immunity to influenza infection and speculate on how the simultaneous evolutionary races of virus and antibody may impact our efforts to design a universal influenza vaccine.
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