Revealing the Complexity of Retroviral Repression
Author(s) -
Gernot Wolf,
Todd S. Macfarlan
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.09.014
Subject(s) - biology , psychological repression , computational biology , genetics , induced pluripotent stem cell , virology , evolutionary biology , gene , embryonic stem cell , gene expression
Retroviral restriction is a complex phenomenon that, despite remarkable recent progress, is far from being well understood. In this Preview, we introduce an insightful study by Yang et al. that represents the first attempt to identify the global determinants of retroviral repression in pluripotent mammalian cells.
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