Open AccessMelatonin Lulling Th17 Cells to Sleep
Author(s) -
Jacob S. Lee,
J. Daniel
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.08.054
Subject(s) - biology , melatonin , circadian rhythm , immune system , sleep (system call) , multiple sclerosis , hormone , disease , endocrinology , medicine , immunology , computer science , operating system
In this issue, Farez et al. report that the circadian hormone melatonin, whose levels vary with seasonal changes in night length, shifts the immune response toward an anti-inflammatory state that may explain the seasonal variability of multiple sclerosis disease activity.
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