Open AccessThe Touching Tail of a Mechanotransduction Channel
Author(s) -
Zachary A. Knecht,
Rachelle Gaudet,
Paul Garrity
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.08.049
Subject(s) - mechanotransduction , biology , neuroscience , ion channel , channel (broadcasting) , sensory system , microbiology and biotechnology , receptor , genetics , computer science , computer network
In mechanotransduction, sensory receptors convert force into electrical signals to mediate such diverse functions as touch, pain, and hearing. In this issue of Cell, Zhang et al. present evidence that the fly NompC channel senses mechanical stimuli using its N-terminal tail as a tether between the cell membrane and microtubules.
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