Open AccessMalaria-Induced B Cell Genomic Instability
Author(s) -
Gerson Rothschild,
A. Nikolai von Krusenstiern,
Uttiya Basu
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.07.051
Subject(s) - biology , genome instability , malaria , virology , genetics , evolutionary biology , immunology , dna , dna damage
Nussenzweig and colleagues evaluate genomic instability and germinal center derived lymphomagenesis in mice infected with Plasmodium to recreate some of the hallmark characteristics of Burkitt lymphoma, a form of cancer more common in parts of Africa where malaria is endemic.
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