Open AccessRemodeling Your Way out of Cell Cycle
Author(s) -
Erdem Sendinc,
Ashwini Jambhekar,
Yang Shi
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.06.050
Subject(s) - biology , microbiology and biotechnology , cell cycle , computational biology , evolutionary biology , cell , genetics
Throughout development, proliferative progenitors lose their mitotic potential, exit the cell cycle, and differentiate. In this issue, Ruijtenberg and van den Heuvel identify an important lineage-specific role for a SWI/SNF chromatin-remodeling complex that collaborates with core cell-cycle regulators to promote cell-cycle exit and terminal muscle cell differentiation.
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