Open AccessBrain Wiring in the Fourth Dimension
Author(s) -
Mathias F. Wernet,
Claude Desplan
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.06.040
Subject(s) - biology , fourth dimension , dimension (graph theory) , neuroscience , evolutionary biology , physics , mathematics , quantum mechanics , spacetime , pure mathematics
In this issue of Cell, Langen et al. use time-lapse multiphoton microscopy to show how Drosophila photoreceptor growth cones find their targets. Based on the observed dynamics, they develop a simple developmental algorithm recapitulating the highly complex connectivity pattern of these neurons, suggesting a basic framework for establishing wiring specificity.
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