Open AccessSnapShot: Intrinsic Structural Disorder
Author(s) -
Mainak Guharoy,
Kris Pauwels,
Péter Tompa
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.05.024
Subject(s) - intrinsically disordered proteins , biology , snapshot (computer storage) , protein structure , protein folding , biophysics , computational biology , microbiology and biotechnology , biochemistry , computer science , operating system
Many proteins (intrinsically disordered proteins, IDPs) or regions of proteins (intrinsically disordered regions, IDRs) lack a well-defined 3D structure under physiological conditions. Albeit unfolded and highly dynamic, these proteins are not denatured; rather, intrinsic structural disorder is their native, functional state.
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