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Treasure Your Exceptions: Unusual Domains in Immune Receptors Reveal Host Virulence Targets
Author(s) -
Marc T. Nishimura,
Freddy Monteiro,
Jeffery L. Dangl
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.05.017
Subject(s) - biology , virulence , host (biology) , immune system , pathogen , receptor , immunosuppression , genetics , computational biology , immunology , gene
A mechanistic understanding of how plant pathogens modulate their hosts is critical for rationally engineered disease resistance in agricultural systems. Two new studies show that genomically paired plant immune receptors have incorporated decoy domains that structurally mimic pathogen virulence targets to monitor attempted host immunosuppression.

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