Open AccessTurning Up the Heat on Membrane Fluidity
Author(s) -
Weiwei Fan,
Ronald M. Evans
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.04.046
Subject(s) - membrane fluidity , biology , lipid bilayer , membrane , membrane lipids , biochemistry , membrane protein , microbiology and biotechnology
How do cells maintain the fluidity of cellular membrane in response to temperature fluctuation? In this issue of Cell, Ma et al. identify a regulatory circuit involving a heat-induced acyl-CoA dehydrogenase that controls the lipid saturation level and the fluidity of cellular membranes by transcriptionally regulating a lipid desaturase.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom