Open AccessFiguring Fact from Fiction: Unbiased Polling of Memory T Cells
Author(s) -
Carmen Gerlach,
Scott Loughhead,
Ulrich H. von Andrian
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.04.038
Subject(s) - biology , figuring , immunological memory , polling , immunization , immunity , immunology , computer science , immune system , physics , optics , operating system
Immunization generates several memory T cell subsets that differ in their migratory properties, anatomic distribution, and, hence, accessibility to investigation. In this issue, Steinert et al. demonstrate that what was believed to be a minor memory cell subset in peripheral tissues has been dramatically underestimated. Thus, current models of protective immunity require revision.
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