Open AccessGradients Are Shaping Up
Author(s) -
Tobias Bollenbach,
CarlPhilipp Heisenberg
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.04.009
Subject(s) - morphogen , biology , morphogenesis , microbiology and biotechnology , developmental biology , anatomy , genetics , gene
In animal embryos, morphogen gradients determine tissue patterning and morphogenesis. Shyer et al. provide evidence that, during vertebrate gut formation, tissue folding generates graded activity of signals required for subsequent steps of gut growth and differentiation, thereby revealing an intriguing link between tissue morphogenesis and morphogen gradient formation.
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