Natural Evolution of Broadly Neutralizing Antibodies | Zendy

Galit Alter | Zendy; Dan H. Barouch | Zendy

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Natural Evolution of Broadly Neutralizing Antibodies

Author(s) -

Galit Alter,

Dan H. Barouch

Publication year - 2015

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2015.04.007

Subject(s) - biology , antibody , virology , natural selection , hiv vaccine , neutralizing antibody , human immunodeficiency virus (hiv) , evolutionary biology , computational biology , selection (genetic algorithm) , genetics , vaccine trial , artificial intelligence , computer science

Wu et al. couple next-generation sequencing with structural analysis to illuminate the key processes that enable the natural evolution and selection of broadly neutralizing antibodies to HIV-1, providing a potential roadmap for the development of HIV-1 vaccine strategies to accelerate the induction of protective antibodies.

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