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Retraction Notice to: A Pleiotropically Acting MicroRNA, miR-31, Inhibits Breast Cancer Metastasis
Author(s) -
Scott Valastyan,
Ferenc Reinhardt,
Nathan Benaich,
Diana Calogrias,
Attila Marcell Szász,
Zhigang C. Wang,
Jane E. Brock,
Andrea L. Richardson,
Robert A. Weinberg
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.03.047
Subject(s) - notice , biology , breast cancer , replicate , microrna , scope (computer science) , regulator , metastasis , computational biology , computer science , cancer , genetics , gene , statistics , political science , law , mathematics , programming language
(Cell 137, 1032–1046; June 11, 2009) Our study reported that miR-31 is a regulator of multiple mRNAs important for different aspects of breast cancer metastasis. We recently identified concerns with several figure panels in which original data were compiled from different replicate experiments in order to assemble the presented figure. The scope of the figure preparation issues includes compiling data from independent experiments to present them as one internally controlled experiment, statistical analyses based on technical replicates that are not reflective of the biological replicates, and comparisons of selectively chosen data points from multiple experiments. As many of the published figures are therefore not appropriate or accurate representations of the original data, we believe that the responsible course of action is to retract the paper. We apologize for any inconvenience we have caused.

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