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SnapShot: Origins of DNA Replication
Author(s) -
Rachel L. Creager,
Yulong Li,
David M. MacAlpine
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.03.043
Subject(s) - replicon , biology , dna replication , origin of replication , eukaryotic dna replication , licensing factor , origin recognition complex , control of chromosome duplication , genetics , snapshot (computer storage) , computational biology , dna re replication , autonomously replicating sequence , genome , dna , gene , computer science , operating system
The fundamental unit of DNA replication, the replicon, is governed by a cis-acting replicator sequence and a trans-activating initiator factor. Despite the increased size and complexity of eukaryotic genomes, eukaryotic DNA replication continues to be guided by the fundamental principles and concepts established in the replicon model.

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