SnapShot: GI Tract Development | Zendy

Patrick S. McGrath | Zendy; James M. Wells | Zendy

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SnapShot: GI Tract Development

Author(s) -

Patrick S. McGrath,

James M. Wells

Publication year - 2015

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2015.03.014

Subject(s) - biology , endoderm , gastrulation , germ layer , pancreas , organogenesis , pdx1 , endocrine system , microbiology and biotechnology , embryo , anatomy , embryogenesis , cellular differentiation , endocrinology , islet , genetics , embryonic stem cell , induced pluripotent stem cell , gene , insulin , hormone

The endoderm germ layer contributes to the respiratory and gastrointestinal (GI) lineages during development, giving rise to an array of specialized epithelial cell types lining organs, including the thyroid, thymus, lungs, liver, biliary system, pancreas, and intestines. This SnapShot timelines and summarizes key stages following gastrulation, including endoderm patterning, organ specification, and organogenesis. A lineage tree of the developing endocrine pancreas is outlined to further illustrate this process.

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