The Hunger Genes: Pathways to Obesity | Zendy

Agatha A. van der Klaauw | Zendy; I. Sadaf Farooqi | Zendy

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The Hunger Genes: Pathways to Obesity

Author(s) -

Agatha A. van der Klaauw,

I. Sadaf Farooqi

Publication year - 2015

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2015.03.008

Subject(s) - obesity , disease , mechanism (biology) , biology , type 2 diabetes , psychological intervention , public health , diabetes mellitus , energy expenditure , bioinformatics , environmental health , medicine , endocrinology , psychiatry , pathology , epistemology , philosophy

The global rise in the prevalence of obesity and associated co-morbidities such as type 2 diabetes, cardiovascular disease, and cancer represents a major public health concern. The biological response to increased consumption of palatable foods or a reduction in energy expenditure is highly variable between individuals. A more detailed mechanistic understanding of the molecular, physiological, and behavioral pathways involved in the development of obesity in susceptible individuals is critical for identifying effective mechanism-based preventative and therapeutic interventions.

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