Open AccessModeling Human Nutrition Using Human Embryonic Stem Cells
Author(s) -
Danny BenZvi,
Douglas A. Melton
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.02.039
Subject(s) - biology , embryonic stem cell , stem cell , microbiology and biotechnology , genetics , gene
Nutrition presents unanswered scientific questions of high public health importance. We envision model systems composed of interacting gastrointestinal and metabolic tissues derived from human embryonic stem cells, populated by gut microbiota. The culture will be embedded in 3D scaffolds, creating a controlled experimental system that enables tissue sampling and imaging.
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