Open AccessA Molecular Take on Aesop’s The Oak and the Reeds
Author(s) -
Corentin J. Moevus,
Eric C. Greene
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.02.036
Subject(s) - biology , nucleosome , polymerase , dna polymerase , dna , genetics , histone
Ngo et al. use single-molecule methods to show that DNA can be more readily displaced from one side of a nucleosome relative to the other side. This unexpected mechanical asymmetry may offer a path of least resistance, allowing RNA polymerases to traverse nucleosomes if they approach from the correct direction.
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