Neural Control of Energy Balance: Translating Circuits to Therapies | Zendy

Laurent Gautron | Zendy; Joel K. Elmquist | Zendy; Kevin W. Williams | Zendy

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Neural Control of Energy Balance: Translating Circuits to Therapies

Author(s) -

Laurent Gautron,

Joel K. Elmquist,

Kevin W. Williams

Publication year - 2015

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2015.02.023

Subject(s) - energy homeostasis , neuroscience , biological neural network , psychological intervention , diabetes mellitus , biology , glucose homeostasis , obesity , balance (ability) , bioinformatics , medicine , endocrinology , insulin resistance , psychiatry

Recent insights into the neural circuits controlling energy balance and glucose homeostasis have rekindled the hope for development of novel treatments for obesity and diabetes. However, many therapies contribute relatively modest beneficial gains with accompanying side effects, and the mechanisms of action for other interventions remain undefined. This Review summarizes current knowledge linking the neural circuits regulating energy and glucose balance with current and potential pharmacotherapeutic and surgical interventions for the treatment of obesity and diabetes.

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