Open AccessGrowing Old with Myc
Author(s) -
Patrick A. Carroll,
Robert N. Eisenman
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.01.018
Subject(s) - biology , longevity , carcinogenesis , oncogene , proto oncogene proteins c myc , genetics , cell , microbiology and biotechnology , cancer research , transcription factor , gene , cell cycle
The Myc proto-oncogene has been intensively studied in tumorigenesis and development. A new paper in Cell reports the role of Myc as a determinant of mammalian longevity. Myc heterozygous mice exhibit extended lifespans resulting from alterations in multiple cellular processes distinct from those observed in other longevity models.
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