Open AccessA Protein Restriction-Dependent Sulfur Code for Longevity
Author(s) -
Hong Seok Shim,
Valter D. Longo
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2014.12.027
Subject(s) - biology , longevity , genetics , code (set theory) , computational biology , set (abstract data type) , programming language , computer science
The restriction of proteins has recently emerged as the most important factor for the beneficial effects of calorie restriction. Hine et al. now provide strong evidence for the role of the hydrogen sulfide (H2S) gas in the protective effects of calorie and protein restriction against ischemia/reperfusion injury (IRI) but also implicate H2S in longevity extension in model organisms.
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