Open AccessDeep, Dark Secrets of Melatonin in Animal Evolution
Author(s) -
Klaske J. Schippers,
Scott Nichols
Publication year - 2014
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2014.09.004
Subject(s) - biology , melatonin , evolutionary biology , genetics , computational biology , neuroscience
Tosches et al. show that melatonin signaling regulates circadian swimming in annelid worms by rhythmically activating cholinergic neurons. This suggests an evolutionary connection between melatonin signaling in invertebrates and sleep regulation in vertebrates.
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