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SnapShot: FMRP mRNA Targets and Diseases
Author(s) -
Emanuela Pasciuto,
Claudia Bagni
Publication year - 2014
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2014.08.035
Subject(s) - biology , rna binding protein , messenger rna , snapshot (computer storage) , fragile x , genetics , rna , fragile x syndrome , binding protein , microbiology and biotechnology , gene , computer science , operating system
FMRP, or fragile X mental retardation protein is an RNA-binding protein. Mutations in the FMRP protein have been associated with neurological disease as have a number of its mRNA-binding targets. This SnapShot presents 40 bona fide FMRP targets for which mRNA binding and protein regulation have been robustly reported in mammals along with the diseases with which they have been associated.

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