Open AccessUnpacking the Unfolded Protein Response
Author(s) -
Carolyn A. Worby,
Jack E. Dixon
Publication year - 2014
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2014.08.025
Subject(s) - endoplasmic reticulum , unfolded protein response , biology , microbiology and biotechnology , secretory protein , secretion , protein folding , secretory pathway , intracellular , biochemistry , golgi apparatus
This year, the Albert Lasker Basic Medical Research Award will be shared by Peter Walter and Kazutoshi Mori for discoveries revealing the molecular mechanism of the unfolded protein response, an intracellular quality control system that detects harmful misfolded proteins in the endoplasmic reticulum and then signals the nucleus to carry out corrective measures.
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