Calorie Restriction à Lamarck | Zendy

Eugene V. Koonin | Zendy

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Calorie Restriction à Lamarck

Author(s) -

Eugene V. Koonin

Publication year - 2014

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2014.07.004

Subject(s) - biology , epigenetics , inheritance (genetic algorithm) , genetics , longevity , nucleic acid , non mendelian inheritance , gene , gene silencing , small interfering rna , calorie restriction , rna , mitochondrial dna , endocrinology

Epigenetic inheritance of resistance to exogenous nucleic acids via small interfering (si) RNA is well established in animal models. Rechavi et al. demonstrate epigenetic inheritance of a starvation-induced pattern of gene silencing caused by endogenous siRNAs and resulting in an increased longevity in the third generation progeny. Combined with recent findings in prokaryotes, these results suggest that Lamarckian-type inheritance of acquired traits is a major evolutionary phenomenon.

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