Open AccessA Slow Dance for Microtubule Acetylation
Author(s) -
F. Jon Kull,
Roger D. Sloboda
Publication year - 2014
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2014.05.021
Subject(s) - biology , acetylation , microtubule , tubulin , acetyltransferase , microbiology and biotechnology , microtubule associated protein , genetics , gene
Microtubules contribute to diverse cellular processes through balancing dynamic, short-lived and stable, long-lived populations. One way in which long-lived microtubules are marked is by posttranslational acetylation of α-tubulin by tubulin acetyltransferase (TAT). Szyk et al. now provide insight into TAT's mechanism of action and its unique time-stamping ability.
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