SnapShot: Epithelial Tight Junctions | Zendy

Karl Matter | Zendy; María S. Balda | Zendy

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SnapShot: Epithelial Tight Junctions

Author(s) -

Karl Matter,

María S. Balda

Publication year - 2014

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2014.04.027

Subject(s) - tight junction , biology , paracellular transport , microbiology and biotechnology , snapshot (computer storage) , cell polarity , epithelial polarity , septate junctions , polarity (international relations) , cell junction , cell , genetics , computer science , membrane , permeability (electromagnetism) , operating system

Tight junctions form a morphological and functional border between the apical and basolateral cell surface domains that serves as a paracellular diffusion barrier, enabling epithelial cells to separate compartments of different composition. Tight junctions also contribute to the generation and maintenance of cell polarity and regulate signaling mechanisms that guide cell behavior, shape, and gene expression. This SnapShot illustrates their components, organization, and functions.

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