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SnapShot: Cancer Vaccines
Author(s) -
Karolina Palucka,
Jacques Banchereau
Publication year - 2014
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2014.03.044
Subject(s) - biology , vaccination , snapshot (computer storage) , immunity , cancer vaccine , immunology , antigen , virology , immune system , immunotherapy , computer science , operating system
This SnapShot illustrates the main concepts and underlying biology of therapeutic vaccination in cancer. Dendritic cells (DCs) are an essential component of vaccination through their capacity to capture, process, and present antigens to T cells. We have come a long way in our understanding of what is needed to elicit therapeutic immunity when cancer escapes the natural barrier of protective immunity. This progress enables the development of novel vaccines.

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