Open AccessInterphase Chromatin LINEd with RNA
Author(s) -
RyuSuke Nozawa,
Nick Gilbert
Publication year - 2014
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2014.02.005
Subject(s) - interphase , biology , chromatin , nuclear matrix , rna , microbiology and biotechnology , genetics , mitosis , chromosome , prophase , cell nucleus , genome , nucleus , dna , meiosis , gene
RNA has been proposed to be a component of an underlying nuclear matrix. Hall et al. show that noncoding, repetitive RNAs, some derived from LINE1 elements, stably associate with interphase chromosomes and copurify with nuclear scaffold, indicating that RNAs might impact interphase chromosome architecture.
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