Open AccessStochastic Responses Are Not Left to Pure “Chance”
Author(s) -
Aggelos Banos,
Marios Agelopoulos,
Dimitris Thanos
Publication year - 2013
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2013.10.002
Subject(s) - biology , chromatin , cooperativity , transcription (linguistics) , genetics , computational biology , transcription factor , gene , chromosome conformation capture , regulation of gene expression , enhancer , linguistics , philosophy
Many coregulated genes assemble in multigene complexes via stochastic inter- and intrachromosomal interactions. In this issue, Fanucchi et al. report that chromatin loop formation governs hierarchical cotranscription within a multigene complex.
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