Open AccessThe Missing Link between Itch and Inflammation in Atopic Dermatitis
Author(s) -
Sarina B. Elmariah,
Ethan A. Lerner
Publication year - 2013
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2013.09.038
Subject(s) - atopic dermatitis , immunology , sensitization , disease , inflammation , immunoglobulin e , cytokine , pathogenesis , dermatology , skin barrier , medicine , biology , pathology , antibody
Atopic dermatitis is a common skin disease with high morbidity and is associated with severe itch and chronic skin inflammation. In this issue of Cell, Wilson et al. demonstrate that epithelial cells communicate directly with cutaneous sensory neurons via a cytokine to induce itch.
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