Open AccessSingular Expression of Olfactory Receptor Genes
Author(s) -
Iván Rodríguez
Publication year - 2013
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2013.09.032
Subject(s) - biology , gene , gene silencing , genetics , olfactory receptor , evolutionary biology , receptor , repertoire , computational biology , neuroscience , physics , acoustics
Understanding the mechanisms of monogenic and monoallelic transcription of the large repertoire of olfactory receptor genes represents a challenging task. A picture is now emerging in which odorant receptor choice and stabilization involve an escape from silencing followed by the activation of an unconventional feedback loop.
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