Open AccessIntrinsic Activity of Odorant Receptors Guides Sensory Map Formation
Author(s) -
John Ngai
Publication year - 2013
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2013.08.037
Subject(s) - olfactory bulb , biology , neuroscience , sensory system , olfactory system , receptor , anatomy , central nervous system , biochemistry
Olfactory sensory neurons innervate the olfactory bulb in stereotyped patterns according to the odorant receptors they express. A study by Nakashima et al. in this issue demonstrates that the odorant receptor's level of intrinsic activity-in the absence of activating odorant-influences the guidance of olfactory axons to their targets.
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