Open AccesslincRNAs: Genomics, Evolution, and Mechanisms
Author(s) -
Igor Ulitsky,
David P. Bartel
Publication year - 2013
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2013.06.020
Subject(s) - biology , genomics , genome , computational biology , vertebrate , functional genomics , comparative genomics , genetics , evolutionary biology , gene
Long intervening noncoding RNAs (lincRNAs) are transcribed from thousands of loci in mammalian genomes and might play widespread roles in gene regulation and other cellular processes. This Review outlines the emerging understanding of lincRNAs in vertebrate animals, with emphases on how they are being identified and current conclusions and questions regarding their genomics, evolution and mechanisms of action.
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