New Balance in Pluripotency: Reprogramming with Lineage Specifiers | Zendy

Uri BenDavid | Zendy; J. Nissenbaum | Zendy; Nissim Benvenisty | Zendy

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New Balance in Pluripotency: Reprogramming with Lineage Specifiers

Author(s) -

Uri BenDavid,

J. Nissenbaum,

Nissim Benvenisty

Publication year - 2013

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2013.04.051

Subject(s) - biology , reprogramming , lineage (genetic) , balance (ability) , cell lineage , genetics , microbiology and biotechnology , evolutionary biology , computational biology , cellular differentiation , cell , gene , neuroscience

Induction of pluripotency in somatic cells has been achieved by myriad combinations of transcription factors that belong to the core pluripotency circuitry. In this issue, Shu et al. report reprogramming with lineage specifiers, lending support to the view of the pluripotent state as a fine balance between competing differentiation forces.

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