Open AccessBeyond DNA: Programming and Inheritance of Parental Methylomes
Author(s) -
Jamie A. Hackett,
M. Azim Surani
Publication year - 2013
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2013.04.044
Subject(s) - biology , reprogramming , epigenetics , genetics , dna methylation , zebrafish , gene , gene expression
Epigenetic reprogramming of parental genomes following fertilization is important to ensure compatibility for totipotency and development thereafter. New studies by Jiang et al. and Potok et al. now demonstrate how the parental DNA methylomes are reset in zebrafish and reveal striking differences from events in mammals.
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