Open AccessThe Cell Biology of Genomes: Bringing the Double Helix to Life
Author(s) -
Tom Misteli
Publication year - 2013
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2013.02.048
Subject(s) - biology , genome , computational biology , evolutionary biology , helix (gastropod) , genetics , cell , microbiology and biotechnology , gene , zoology , gastropoda
The recent ability to routinely probe genome function at a global scale has revolutionized our view of genomes. One of the most important realizations from these approaches is that the functional output of genomes is affected by the nuclear environment in which they exist. Integration of sequence information with molecular and cellular features of the genome promises a fuller understanding of genome function.
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