Open AccessQuit Stalling or You’ll Be Silenced
Author(s) -
Karen S. Kim Guisbert,
Erik J. Sontheimer
Publication year - 2013
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2013.02.025
Subject(s) - biology , biogenesis , rna , genetics , gene , small rna , cryptococcus neoformans , genome , computational biology , microbiology and biotechnology
The use of small RNAs to program gene regulation and genome defense necessitates ever-changing choices about the sequences used for small-RNA biogenesis. Dumesic et al. now reveal stalled spliceosomes as a trigger for small-RNA biogenesis in the pathogenic fungus Cryptococcus neoformans.
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