Retraction Notice to: Enhanced Polyubiquitination of Shank3 and NMDA Receptor in a Mouse Model of Autism | Zendy

Muhammad Bangash | Zendy; Joo Min Park | Zendy; Tatiana Melnikova | Zendy; Dehua Wang | Zendy; Soo Kyeong Jeon | Zendy; Deidre Lee | Zendy; Sbaa Syeda | Zendy; Juno Kim | Zendy; Mehreen Kouser | Zendy; Joshua L. Schwartz | Zendy; Yiyuan Cui | Zendy; Xia Zhao | Zendy; Haley E. Speed | Zendy; Sara E. Kee | Zendy; Jian Cheng Tu | Zendy; Jiahua Hu | Zendy; Ronald S. Petralia | Zendy; David J. Linden | Zendy; Craig M. Powell | Zendy; Alena Savonenko | Zendy; Bo Xiao | Zendy; Paul F. Worley | Zendy

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Retraction Notice to: Enhanced Polyubiquitination of Shank3 and NMDA Receptor in a Mouse Model of Autism

Author(s) -

Muhammad Bangash,

Joo Min Park,

Tatiana Melnikova,

Dehua Wang,

Soo Kyeong Jeon,

Deidre Lee,

Sbaa Syeda,

Juno Kim,

Mehreen Kouser,

Joshua L. Schwartz,

Yiyuan Cui,

Xia Zhao,

Haley E. Speed,

Sara E. Kee,

Jian Cheng Tu,

Jiahua Hu,

Ronald S. Petralia,

David J. Linden,

Craig M. Powell,

Alena Savonenko,

Bo Xiao,

Paul F. Worley

Publication year - 2013

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2012.12.039

Subject(s) - ubiquitin , biology , nmda receptor , notice , blot , western blot , receptor , genetics , microbiology and biotechnology , computational biology , gene , political science , law

Our paper reported an analysis of a mouse genetic model that deletes the C terminus of Shank3 to mimic human mutations that cause autism spectrum disorder. Figure panels for several polyubiquitination assays were improperly assembled, leading to multiple repetitions of bands in western blots of the lysates. These errors did not affect the quantitative analysis of polyubiquitination because this analysis was performed as described and was not dependent on representative western blot images. In light of the figure preparation issues, we feel that the most responsible course of action is to retract the paper. We sincerely apologize to the scientific community for any misunderstanding that these errors may have caused.

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