Open AccessModeling Transcriptome Dynamics in a Complex World
Author(s) -
Philipp A. Jaeger,
Colleen J. Doherty,
Trey Ideker
Publication year - 2012
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2012.11.031
Subject(s) - biology , transcriptome , dynamics (music) , computational biology , evolutionary biology , genetics , gene expression , gene , physics , acoustics
An accurate prediction of how extrinsic stimuli influence changes in gene expression has been challenging. In this issue, Nagano and colleagues successfully model genome-wide mRNA expression changes under variable environmental conditions in rice, raising hopes that scientists will soon be able to predict genome-wide transcriptional responses in a variety of organisms in uncontrolled real-world settings.
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