Shedding Light on Apoptosis at Subcellular Membranes | Zendy

Justin Kale | Zendy; Qian Liu | Zendy; Brian Leber | Zendy; David W. Andrews | Zendy

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Shedding Light on Apoptosis at Subcellular Membranes

Author(s) -

Justin Kale,

Qian Liu,

Brian Leber,

David W. Andrews

Publication year - 2012

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2012.11.013

Subject(s) - biology , microbiology and biotechnology , mitochondrion , cytoplasm , programmed cell death , translocase of the inner membrane , vesicle associated membrane protein 8 , mitochondrial membrane transport protein , apoptosis , intermembrane space , mitochondrial intermembrane space , bcl 2 family , membrane protein , bacterial outer membrane , inner mitochondrial membrane , biochemistry , membrane , gene , escherichia coli

Regulation of apoptosis by Bcl-2 family proteins is a paradigm for complex protein-protein and protein-membrane systems. Elucidating the molecular mechanisms of these interactions in vitro in live cells and in animal studies has been significantly enhanced by using fluorescence techniques.

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