Open AccessPoxvirus Use a “Gene Accordion” to Tune Out Host Defenses
Author(s) -
John R. Roth,
Dan I. Andersson
Publication year - 2012
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2012.07.026
Subject(s) - biology , host (biology) , gene , accordion , genetics , virology , world wide web , computer science
A multistep process of gene amplification, mutation, and reduction allows poxvirus to overcome host antiviral defenses. The mechanism speeds genetic adaptation and promises to be broadly applicable in many biological settings.
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