A piRNA to Remember | Zendy

Danesh Moazed | Zendy

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A piRNA to Remember

Author(s) -

Danesh Moazed

Publication year - 2012

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2012.04.008

Subject(s) - biology , piwi interacting rna , aplysia , transposable element , germline , silence , genetics , neuroscience , gene , evolutionary biology , microbiology and biotechnology , genome , philosophy , aesthetics

In this issue of Cell, Rajasethupathy et al. report a surprising role for piRNAs, previously thought to act mainly in the animal germline to silence transposons, in transcriptional regulation of plasticity-related genes in the central nervous system of the sea slug Aplysia californica. The findings expand the functions of small RNAs and have important implications for our understanding of how transient signals can give rise to long-term memories.

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