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High-Speed AFM Reveals the Dynamics of Single Biomolecules at the Nanometer Scale
Author(s) -
Allard J. Katan,
Cees Dekker
Publication year - 2011
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2011.11.017
Subject(s) - biomolecule , nanotechnology , nanometre , atomic force microscopy , biology , millisecond , angstrom , resolution (logic) , visualization , nanoscopic scale , materials science , biophysics , computer science , physics , chemistry , data mining , artificial intelligence , astronomy , composite material , crystallography
Atomic force microscopy allows visualization of biomolecules with nanometer resolution under physiological conditions. Recent advances have improved the time resolution of the technique from minutes to tens of milliseconds, meaning that it is now possible to watch single biomolecules in action in real time. Here, we review this development.

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