Open AccessIs iNOS Beginning to Smoke?
Author(s) -
Carl Nathan
Publication year - 2011
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2011.09.031
Subject(s) - nitric oxide synthase , biology , pulmonary disease , nitric oxide , atp synthase , disease , copd , bioinformatics , enzyme , medicine , biochemistry , endocrinology
Inducible nitric oxide synthase (iNOS) helps drive numerous inflammatory disorders, but its inhibition has not had therapeutic success. Now Seimetz et al. (2011) make a case for inhibiting iNOS in an effort to treat one of the world's leading causes of death-chronic obstructive pulmonary disease.
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