Open AccessElongated Membrane Zones Boost Interactions of Diffusing Proteins
Author(s) -
Joshua Zimmerberg,
Samuel T. Hess
Publication year - 2011
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2011.08.003
Subject(s) - biology , membrane protein , membrane , lipid bilayer , cell membrane , lipid raft , biological membrane , microbiology and biotechnology , biochemistry
Biological membranes are two dimensional, making the discovery of quasi-one-dimensional diffusion of membrane proteins puzzling. Jaqaman et al. (2011) now show that actomyosin and tubulin interact to establish long, thin diffusion corridors, thereby increasing the effective concentration of select membrane proteins to promote their interactions and modulate signaling.
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