Open AccessPrivileged Signaling for Brain Growth
Author(s) -
Aurelio A. Teleman
Publication year - 2011
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2011.07.010
Subject(s) - biology , signal transduction , microbiology and biotechnology , drosophila (subgenus) , neuroscience , insulin receptor , kinase , receptor , computational biology , genetics , insulin , gene , insulin resistance
When developing animals encounter nutrient restriction, most tissues stop growing. Some vital tissues, however, such as the brain, continue to grow. Now, Cheng et al. (2011) identify Alk as the kinase that allows the Drosophila brain to continue growing during nutrient restriction by bypassing the requirements for insulin receptor and TOR activation.
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